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Additionally, the activation of microglia and astrocytes in ALS leads to the production of ROS and pro-inflammatory cytokines, further exacerbating oxidative damage and motor neuron degeneration [170]

in a prospective study of 200 patients were first to demonstrate the association of elevated cell-free, plasma mtDNA levels with increased ICU-related mortality

Fertil Steril 79:292300 Mansour G, Abdelrazik H, Sharma RK, Radwan E, Falcone T, Agarwal A (2009) L-carnitine supplementation reduces oocyte cytoskeleton damage and embryo apoptosis induced by incubation in peritoneal fluid from patients with endometriosis

Kowaltowski and Fiskum, 2005

The plasma membrane glutamine transporters SLC6A14, SLC7A11, and SLC38A1 have been targeted and found to be inhibited by erastin, -Me-Trp, and MeAIB, respectively (Fig