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Compared to the original drug, bioavailability was significantly improved, providing a valuable basis for subsequent research

(2) synthesis of the polyisoprenoid side chain from acetyl-coenzyme A (CoA) via the mevalonate pathway

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World J Gastroenterol 24:139149

When scaled to human-equivalent doses using standard allometric conversion factors, this translates to approximately 1.6-3.2 g/kg, or roughly 120-240 g for a 75kg subject
