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Pardaxin permeabilizes vesicles more efficiently by pore formation than by disruption

113 Vesna et al

The authors noted a non-significant trend towards a lower incidence of liver transplantation in the treatment group and a significant increase in the incidence of nausea and vomiting as the main side effect

Some of these changes may be secondary consequences of the oxidativestress-dependent inflammatory response that develops with time under long-standing pro-oxidant conditions, the hepatic accumulation of toxic biliary solutes due to the secretory failure (e.g