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DEM (420 mm, 0.25 ml) in oil was administered intrarectally and colonic tissue examined over time (1, 4 and 24 hours) for GSH levels and injury

Ergebnisse Eine direkte Bewertung des Blutdrucks in der Portalvene zeigte eindeutig, dass NaBPC157 sowie Propranolol (verabreicht bei smtlichen Regimen) die ansonsten erhhten portalen Blutdruckwerte in den Kontrollratten verhinderte und/oder deutlich senkte

10.1371/journal.pone.0094792 83 LiY.ChenT.MiaoX.YiX.WangX.ZhaoH.et al (2017)

They promote lipid, protein, and DNA oxidation, forming cytotoxic products such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), which compromise mitochondrial DNA and disrupt electron transport, especially at complexes I and III (Wang et al., 2024)

Aging 58, 163179