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[DOI] [PMC free article] [PubMed] [Google Scholar] 412

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notably, this is the only NAD + synthesis pathway that operates independently of niacin [17]

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Dosages start at 500 mg/day and are often gradually increased to as high as 3000 mg/day for immediate release or 2000 mg/day for slow release (also referred to as sustained release) to achieve the targeted lipid changes (lower LDL-C and triglycerides, and higher HDL-C)

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