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Aliquots (~0.1 mg) of the target compounds were dissolved in methanolic KOH solution (1.2 mol/L, 80% MeOH), incubated at 50 C for 2 h, then adjusted to pH 5.0 and analyzed by means of UPLC-TOF MS in the negative electrospray mode

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The names of the repository/repositories and accession number(s) can be found below: Ethics statement The animal study was reviewed and approved by the Institutional Animal Care and Use Committee of Guangxi Medical University