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Cristaldi, V

Most tumors were located at a single level (n = 52, 82.5%)

The pigmentary lesions are light to dark brown macules and patches that may be segmental and tend to be unilateral

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C3d was first used as an adjuvant in 1996, with 2 or 3 copies of recombinant C3d delivered alongside the model antigen HEL, drastically increasing antibody responses by up to 10,000-fold (145)

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