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However, this process is gradual and relies on consistent, high-quality supplementation

doi: 10.1007/s00702-018-1952-7

[DOI] [PMC free article] [PubMed] [Google Scholar] 126.El Hayek E

Blood (2004) 103(4):1398407.10.1182/blood-2003-07-2617 148 TsuiFWMartinAWangJTsuiHW

Consistently, postmortem striatal brain tissue from three patients with PD exhibited elevated FTH1 and IL-8 expression, closely recapitulating the transcriptional profile of microglia in the in vitro model

The first hit is insulin resistance, causing increased uptake and synthesis of free fatty acids that are subsequently stored as triglycerides, resulting in simple steatosis