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Research suggests combining both mechanisms produces additive or synergistic satiety effects beyond either pathway alone

Liu et al., 2011), where it is needed to metallate numerous enzymes, and it has the capacity to oxidize thiols
Stiede, K

ESG risk factors can be included too
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Holotranscobalamin, a marker of vitamin B 12 status: analytical aspects and clinical utilityAm J Clin Nutr2011;94:359S-65S
