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Promiscuous binding of proinsulin peptides to type 1 diabetes-permissive and -protective HLA class II molecules

Take atherosclerosis as an example, we have known that plaques composed of fat and protein gradually accumulate on the inner arterial wall, which is prone to cause coronary atherosclerotic disease, stroke, or other ischemic severe diseases

doi: 10.2217/epi.11.71

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Potential Role of Natural Polyphenols Against Protein Aggregation Toxicity: In Vitro, In Vivo, and Clinical Studies. ACS Chemical Neuroscience 11: 29152934

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