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Los medicamentos para tratar infecciones resultan los principales implicados en el sntoma, como los siguientes: Nitrofurantona Cloroquina y primaquina (antipaldicos) En el contexto de un tratamiento para la malaria, el color oscuro de la orina, entre rojo negruzco y marrn, puede atribuirse a los antipaldicos, como sostiene un estudio desarrollado por la Universidad de Antioqua