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Nevertheless, studies conducted on animals revealed that administering garlic at doses of 450, 900, and 1,350 mg/kg for 26 days caused a significant decrease in body weight, suggesting that the advantages were more pronounced in animal models (124)

MKP-1, mitogen-activated protein kinase phosphatase-1

Composed of three amino acidsglutamate, cysteine, and glycineit is the most abundant non-protein thiol in mammalian cells, where it exists in two primary states: the reduced form (GSH) and the oxidized form, glutathione disulfide (GSSG)

(Peck 2021) Metabolism : Phenytoin is metabolized in the liver via CYP 2C9 (~90%) and, to a lesser extent, 2C19 (~10%)

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