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Further in vitro and in vivo experiments uncovered metformins ability to suppress oxidative stress by promoting the expression of Nuclear factor erythroid 2-related factor 2 (Nrf2)

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A total of 32 Wistar albino rats were separated into four groups: control, RAD (10Gy once on 1st day), RAD+LCAR (intraperitoneally, 200mg/kg/d, for 10days), and LCAR

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This can lead to build up of toxins in the liver and other organs, damage to cells requiring more cellular repair, and the inability of energy production