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E.LiuS.YuJ.et al (2009)

Higher-than-required dosages can lead to severe side effects like kidney failure or blood poisoning

It is important to relieve abdominal pain with a parenterally administered narcotic medication
therefore, they may attack RBCs, inducing membrane structure changes (erythrocyte shrinkage, membrane blebbing, and PS exposure) and, finally, eryptosis

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