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Isatuximab interacts with a discontinuous epitope partially overlapping the catalytic site, whereas Daratumumab binds to two continuous amino acid sequences situated outside the enzymatic active site of CD38 (52, 53)

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Potency compared to BDNF In preclinical research, Dihexa has been described as potentially millions of times more potent than BDNF (brain-derived neurotrophic factor) in driving synapse growth