glutathione s-transferase alpha 4 Transferase - an overview Frontiers | DNA methylation and
Description
In tumor microenvironments, amino acids such as arginine and tryptophan can be limiting (Sullivan et al, 2019), and as we found here for Arg and Leu, a quiescent-like state is enforced when these AAs are deprived

This percentage will be even less in more acidic compartments such as the vacuole or apoplast, although GSH concentrations are relatively low at these locations

doi: 10.1080/21688370.2016.1251384

In the same study, these authors reported that indoxyl sulfate provokes the enhancement of ceramide levels, which is another well-recognized eryptosis-contributing factor [253]

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