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Data Extraction Two researchers read the full texts independently and extracted the following contents: publication data (first author's name, year of publication), study characteristic (study design, sample size, follow-up duration, inclusion criteria, and endpoints), patient characteristics (age, gender, NYHA classification, cardiac histology, and LVEF), treatment protocol (L-C dose), and outcome measures (all-cause mortality, overall efficacy, NYHA classification, 6-minute walk, LVEF, SV, CO, E/A, LVEDD, LVESD, LVESV, BNP, NT-proBNP, and adverse events)

In response to cold conditions and excessive food intake, WAT lipolysis promotes acylcarnitine production in the liver

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Viral infections such as the flu cause acute inflammation, and proinflammatory cytokines such as interleukin (IL) -1 or antiviral cytokines including interferons (IFNs) are made in the environment by activating Toll-like receptors

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