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Acknowledgements This manuscript was funded by National Nature Science Foundation of China (No

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Food Chem X 14:100343 Lu X, Zeng R, Lin J, Hu J, Rong Z, Xu W, Liu Z, Zeng W (2019) Pharmacological basis for use of madecassoside in gouty arthritis: anti-inflammatory, anti-hyperuricemic, and NLRP3 inhibition

Weight training preserves muscle mass, maintains metabolic rate, and improves body composition beyond what the scale shows

Examples of genetic defects inducing redox dysregulation and hemolytic anemia are the genetic deficiency of G6PDH (well-characterized human disease) and the genetic deficiency of antioxidant enzymes, including SOD1 and 2, Prx1 and 2, and nuclear factor E2-related factor 2 (Nrf2, a transcription factor controlling expression of multiple antioxidant and detoxifying enzymes)