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URL: Hydramed

PMID: 23994746

Brucein D, a naturally occurring quassinoid, enhances the sensitivity of pancreatic ductal adenocarcinoma (PDAC) cells to gemcitabine (GEM) by promoting the ubiquitin-proteasome-dependent degradation of NRF2 and suppression of the NRF2 signaling pathway [104]

Another, smaller scale study found similar results in bovine ticks that had been selected for ivermectin resistance (through exposure to sublethal doses of ivermectin) after analysing the ABC transporter transcriptome, where they also found that these genes were significantly upregulated (Pohl et al

Lactobacillus plantarum probiotics encapsulated with whey were better protected from the harsh conditions of the digestive system

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