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Others choose lower concentrations (like 2.5 mg/mL) to allow more precise measurement of small doses

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[DOI] [PubMed] [Google Scholar] Schmidt CJ, Sullivan CK, Fadayel GM

The problem with carnitine Muscle takes up carnitine against a very large (about 1,000-fold) concentration gradient (plasma carnitine is 40-60 mol/L and muscle carnitine is 4-5 mmol/L)

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Although several genes such as Fgf21 (Figure 2C), Pdk4 , and Acot2 showed a modest suppression in their induction upon the loss of Atgl in Cpt2 L/ mice, most genes in DKO mice resembled the response of Cpt2 L/ mice (Figure 4A)