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Mean weight reductions from baseline at week 26 were dose-dependent for Cagrilintide

LL-37 is part of the innate immune system and influences: Antimicrobial defense Inflammatory signaling Immune modulation Skin healing Abnormal processing of LL-37 has been implicated in rosacea pathophysiology

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10.1111/j.1432-1033.1997.00710.x 9 BenjaminN.ODriscollF.DougallH.DuncanC.SmithL.GoldenM.et al (1994)

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Biomarker performance was evaluated using receiver operating characteristic (ROC) curve analysis based on exploratory multivariate models, calculating area under the curve (AUC), sensitivity, and specificity