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Human growth hormone (HGH)

Excessive intake may cause diarrhea, nausea, or low blood pressure

Enterocytes line the gastrointestinal tract and M cells are primarily located within the epithelium of Peyers patches

Mutations in these regions alter the GDH antenna-like domain and weaken the binding capacity of GTP binding domains with GTP, thereby compromising the inhibitory effect of GTP on GDH activity

2021;3:rgab038
