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Physiol Behav 100:525534 Wakahara S, Konoshita T, Mizuno S, Motomura M, Aoyama C, Makino Y, Kato N, Koni I, Miyamori I (2007) Synergistic expression of angiotensin-converting enzyme (ace) and ace2 in human renal tissue and confounding effects of hypertension on the ace to ace2 ratio

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Using flies and mice, it has been demonstrated that sleep deprivation results in the accumulation of ROS with consequent oxidative stress in the gut, rather than in the brain (Vaccaro et al

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Interestingly, finasteride also inhibits the activity of steroid 5-reductase, a soluble steroid reductase that belongs to the NADPH-dependent aldo-keto reductase (AKR) superfamily 43