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Although the levels of demethylation during the pre-implantation period are significant, a portion of DNA methylation will be kept during the reprogramming after fertilization, including the imprinted genes, which represent an inheritance from the paternal environment to the offspring phenotype (Jiang et al., 2018)

Furthermore, changes in body composition, particularly with regard to muscle mass, may have influenced the energy expenditure findings, highlighting the need for longer-term studies to fully assess the effects of GLP-1 analogs on metabolism

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Molecular characteristics, clinical significance, and cancer immune interactions of cuproptosis and ferroptosis-associated genes in colorectal cancer

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