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Alpha synuclein binds to iron, which accelerates its aggregation into fibrils

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He Z, Kong W, Zou S, Huang H, Sha S
The nuclear factor erythroid 2-related factor 2 ( NFE2L2 or NRF2) transcription factor is constitutively activated in many cancers and promotes a specific gene expression program involved in cellular detoxification, redox buffering, and metabolic rewiring (Cancer Genome Atlas Research, 2012

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