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GPX4 is essential for embryonic development
That said, more is not always better
The consumption of spinach should be limited, because it contains fairly high levels of oxalic acid , an organic compound that may cause calcium deficiency or kidney stones in large doses
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doi: 10.1136/gut.22.8.663 218 QosaHAvarittBRHartmanNRVolpeDA
Several antibiotics (e.g., penicillins, fluoroquinolones, tetracyclines) can either inhibit the synthesis of vitamins, decrease absorption, or form insoluble complexes decreasing the bioavailability of various minerals and vitamins (126)
