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TMAO circulating values of all MetaCardis participants were log 10 -transformed, and subsequently the median was subtracted and divided by the standard deviation 23 (SD

Discussion Consistent with observational studies and systematic review and meta-analysis of RCTs [5, 14], our study suggests no benefit of l-carnitine for CVD or its risk factors

participants should not adjust their dose independently Antiemetics : A clinician may consider short-term antiemetic treatment if nausea is significant For concerns related to muscle mass preservation , incorporating resistance exercise and ensuring adequate dietary protein intake are evidence-based strategies that may help mitigate lean tissue loss during significant weight reduction