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An olive-derived extract 20% rich in hydroxytyrosol prevents -amyloid aggregation and oxidative stress, two features of Alzheimer disease, via SKN-1/NRF2 and HSP-16.2 in Caenorhabditis elegans

Desensitization of insulin secretion

Fossum et al., 2022), suggesting that restoring GSH levels would reduce viral entry and SARS-CoV-2 cellular infection

Some natural compounds with antioxidant properties that are isolated from medicinal plants have also been shown to protect against ovarian aging through multiple mechanisms (Xu X et al., 2017)

The protocol for hidden platform testing has been described in detail elsewhere [16]

As such, the following BERs could be calculated per benchmark chemical-exposure scenario (see Table 3 ) and upper and lower respiratory tract tissue model (i.e