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You need to have an intrinsic factor, a protein made by cells in your gut lining to bring B12 into circulation, transcobalamin proteins to move it around the body and finally, pancreatic enzymes for absorption

Beef liver offers similarly impressive amounts, with around 6070 micrograms per 100g

Summary: Vitamin B12 supplements for pregnancy are recommended for vegans, vegetarians, and women with absorption disorders, typically at 50-150 micrograms daily for dietary deficiency or intramuscular injections for malabsorption

While the timeline varies for each person, it typically takes a few days or weeks before vitamin B12 levels improve, reducing symptoms such as extreme tiredness or lack of energy

This is studied separately from its telomere-related effects and is one reason Epithalon is investigated in ageing models, where circadian and melatonin signalling are of interest

I had been fine using the out of date B12 (04/2022) until I suspect a couple of months ago when I began feeling a fair bit weaker, more noticeable to me when out cycling