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Modulation of anxiety through blockade of anandamide hydrolysis

4 Trauma and post-inflammatory pigmentation Any repeated micro-trauma to a specific point on the lip (a habitual lip-biting spot, friction from a tooth, a healed cold sore, an old burn from hot food or drinks) can trigger localized post-inflammatory hyperpigmentation that stabilizes into a melanotic macule

The imaging parameters were as follows: T1-weighted images: repetition time (TR) 500600 ms, echo time (TE) 1520 ms

doi: 10.3389/fphar.2014.00038

After stopping MT-II, the tan persists 4-8 weeks and fades gradually as melanocytes turn over naturally