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However, those questions remain largely unanswered at the human level

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I cover its natural role in plasma and tissues, how levels fall with age, and the surprising breadth of its actionsfrom extracellular matrix remodeling and antioxidant effects to cognitive protection, cardiovascular benefits, and boosted wound healing

[DOI] [PMC free article] [PubMed] [Google Scholar] 454.Booth D.M., Enyedi B., Geiszt M., Vrnai P., Hajnczky G

The mutations in cystinosin associated with the most severe form of cystinosis also poorly recruit mTOR to the lysosome [127]