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10.3390/antiox12112012 131 SiavashyS.SoltaniM.Ghorbani-BidkorbehF.FallahN.FarnamG.MortazaviS

However, there is currently no cure for the condition, and due to the variability in how the disease presents itself, some symptoms may not respond effectively to these treatments

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OA chondrocytes displayed reduced mitochondrial DNA content, mitochondrial dysfunction, and diminished expression of NRF2 which regulates the transcription of oxidoreductase genes 89