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Carnosine and -alanine levels may vary with age

66 The reduction of nitrosamines ( 1 ) to 1,1-disubstituted hydrazines ( 27 , Figure 3) has been known since the late 19th century 67 and can be effected with a wide variety of reaction conditions

[DOI] [PMC free article] [PubMed] [Google Scholar] 334.Gonzalez-Lopez A, Lopez-Alonso I, Pickerodt PA, von Haefen C, Amado-Rodriguez L, Reimann H, Niendorf T, Kuebler W, Albaiceta GM, Francis RCE, Spies CD

Chondrocytes, the only cellular component of cartilage, maintain the dynamic equilibrium of the extracellular matrix (ECM) through precise regulation of collagen type II and matrix-degrading enzyme secretion ( In mouse models of OA, typical characteristics of ferroptosis have been observed in chondrocytes, including abnormal iron metabolism, lipid peroxidation, and mitochondrial dysfunction (Yao et al., 2021)