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Authors observed that AMDs retinal pigment epithelium (RPE) contains less dense cytoplasm, more lipid droplets, increased glycogen granules, and enlarged autophagosomes [129]

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DHA is selectively incorporated into retinal and neuronal cell membranes (91, 92), suggesting it plays important roles in vision and nervous system function

Monocyte and macrophages numbers rise in the cerebral cortex as a result, and the immune cells microglia in the parenchyma are activated [53]

We found proteomic signatures, which indicated that the pathways associated with the cell scavenger function were highly enriched in the PNCs and factors specific to efficient glycan degradation were abundant (e.g