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Description
Crossref 45
AOD9604 is not approved for human use, but is used in sport for weight loss and muscle enhancement and the perception that it helps recover from tissue damage
Quick Answer: The largest Phase IIb trial (536 subjects, 24 weeks) did not hit statistical significance for weight loss ending commercial development in 2007
[14] Crabtree MJ, Channon KM
Appl Microbiol Biotechnol 20:88378857
In fact, down-regulation of mitochondrial Grx2 is linked to decreased Complex I activity [140], presumably due a to a reduction of deglutathionylation [28]
