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Western blot assays showed that no significant alteration in the expression of SLC7A11 was observed in VRK2-downregulating PC cells (Fig

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Notably, Nrf2 plays a dual protective role by both repressing neuroinflammatory signaling and promoting the transcription of antioxidant genes, establishing it as a compelling therapeutic target in neurodegenerative disorders [182, 183]

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A critical lifesupporting role for cystathionine lyase in the absence of dietary cysteine supply