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Description
While this dose is considerably higher than typical environmental residues (found in the range of micrograms per kilogram), it is intentionally used in high-dose toxicological models to elucidate mechanisms of toxicity and assess mitigation strategies under controlled conditions 41
It cannot be ruled out that the NBD-moiety affects the properties of the lipid analogs used here and, therefore, the binding properties that were measured

Instead of pushing the body into overdrive through the central nervous system, L-carnitine works quietly in the background, helping transport fatty acids into the mitochondria , where they can be burned as fuel
[PUBMED Abstract] Binni F, Antigoni I, De Simone P, et al.: Novel and recurrent p14 mutations in Italian familial melanoma

The assay was performed according to the GAGO-20 kit protocol
[PMC free article: PMC2879499] [PubMed: 20228404] 669
