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doi: 10.1001/jama.2021.3854

We also recently highlighted the implication of cilia in the FlnA KI rat model developing myxomatous MVP ( Endothelial-to-mesenchymal transition (EMT) Happening at embryonic stage E9.5 in mice, EMT relates to the transition of endocardial cells to mesenchymal cells, and their simultaneous migration into the cardiac jelly during development to subsequently remodel ECM and give rise to valvular structure (7982)

Rosadini G, Marenco S, Nobili F, et al

Nasca D, Zurria G, and Aguglia E

Introduction Age-related macular degeneration (AMD) is a leading cause of vision impairment and blindness, particularly among older adults worldwide

Consequently, late-stage interventions remain largely reactive, aimed at halting further deterioration rather than restoring vision or addressing upstream disease mechanisms
