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In particular, note the increase of glutathione S transferases, enzymes involved in detoxification processes

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The experimental group was administered a daily subcutaneous injection of 60 mg/kg body weight of dehydroepiandrosterone (DHEA

[DOI] [PMC free article] [PubMed] [Google Scholar] 627.Brown RB, Tozer DJ, Egle M, Tuladhar AM, De Leeuw F-E, Markus HS

Thus, GliN-mediated N-methyltransferase is the prerequisite for the cytotoxicity of gliotoxin, whereas the GtmA-mediated S-methylation plays an important role in the detoxification of gliotoxin [112]
