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Pathway of Intranasal Transport to the Brain The motivation for developing intranasal drug administration stems from the challenge of delivering drugs to the brain while overcoming the Blood-Brain Barrier (BBB)

The experimental identification and characterization of transporters are currently both expensive and time-consuming

Although the body produces it naturally, factors like stress, poor diet, ageing, pollution and illness can reduce its levels, making supplementation helpful for many individuals

If DSIP enhances deep sleep, it could theoretically amplify this natural hormone release window

10.1073/pnas.0608175103 127 Cuevas-VelazquezC