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In addition, the study of CV3-1 used a larger infectious dose of SARS-CoV-2 (10 5 focus-forming units compared with 10 3 plaque-forming units), leading to increased viral burden and more acute disease progression

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[DOI] [Google Scholar] Stoyanovsky D

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As with all research compounds, investigators should implement appropriate laboratory safety protocols and follow institutional guidelines for handling investigational chemical compounds in controlled research environments