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These findings suggest that accelerated loss of GSH can occur under oxidative stress, in part, due to GPx-1-mediated reduction of peroxides

In 2016, this classification was updated in order to include molecular findings such as diagnostic biomarkers and prognostic factors (5)
Yu J, Hu Y, Xue M, Dun Y, Li S, Peng N, Liang Y, Zhao S (2016) Purification and identification of antioxidant peptides from enzymatic hydrolysate of Spirulina platensis
Growing evidences suggest that a single genetic factor is unlikely to adequately predict the efficacy and toxicity of MTX in polygenic disease, such as RA and autoimmune associated ocular disease

Smith JF, Shindel AW, Huang YC, et al
Nature and site of phospholamban regulation of the Ca 2+ pump of sarcoplasmic reticulum