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Yousefi S, Perozzo R, Schmid I, Ziemiecki A, Schaffner T, Scapozza L, et al

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MOTS-c and 5-Amino-1MQ target upstream metabolic pathways (AMPK activation and NAD+ preservation) that enhance energy expenditure and fat oxidation independent of appetite or intake

Both proteins can be in turn reduced back to their active form, directly by GSH or indirectly by NADPH ( Melatonin ( N -acetyl-5-methoxytryptamine, Figure 5) is a neurohormone derived from amino acid tryptophan

A., & Azer, S

ACSS2: Acetyl-CoA synthetase 2
