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A recent study showed that HBx inhibits the cGAS-STING pathway through autophagic degradation of cGAS [60]
Oxidative stress occurs when there is an imbalance between free radicals and antioxidants in the body, resulting in cellular damage
However, anthocyanin levels in the most commonly eaten fruits and vegetables may be inadequate to confer optimal benefits
Therefore, comprehensive interventions targeting the "muscle-liver axis" (e.g., nutritional and exercise therapies) can provide multi-target strategies for MASLD/MASH by modulating these mechanisms [123]
World Journal of Gastrointestinal Endoscopy
