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Practical points (dose-related) Dilute and give IV slowly to avoid anaphylaxis

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Payers want to see that the prescriber is following the FDA-approved escalation protocol: starting at 2.5mg weekly for 4 weeks, then increasing to 5mg weekly, with subsequent increases as clinically indicated

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B12 support tends to interest people who feel their tank runs low and want a clinician to look at whether a nutrient gap is part of the picture

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