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Satyanarayana A, Balakrishna N, Pitla S, Reddy PY, Mudili S, Lopamudra P, et al

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Solution structures of covalent adducts have been deposited for compounds bound to protein targets [152,153,154] but also to minor groove duplex DNA: for example, the covalent adduct of chemotherapy drug mitomycin C (UGN-101) with a DNA 9-mer (PDB: 199D) [155] and the alkylating agent duocarmycin A covalently bound to a DNA 7-mer (PDB: 107D) [156]