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Administration of MS-275, an HDAC inhibitor, also increases expression of mGlu2 receptors, supporting the role of epigenetic mechanisms in the regulation of mGlu2 receptors [30]

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Blots were developed with SuperSignal West Femto Maximum Sensitivity Substrate (Thermo Scientific)

Gilchrist CLM

Medicinal herbs and bioactive compounds overcome the drug resistance to epidermal growth factor receptor inhibitors in non-small cell lung cancer

74 Accordingly, decrease in Schirmers I test result is more significant in patients with dry eye associated with SARDs comparatively to those without SARDs, suggesting a more significant dysfunction/destruction of the lacrimal glandular tissue in the first group