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The data generated during this phase help define the dose range that may be explored in subsequent studies and contribute to understanding exposure-response relationships, pharmacokinetic behavior and safety considerations associated with the investigational compound

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As expected the results shown in Figure 37 indicate that dihexa significantly improved performance (p 0.05) indicating that the newly formed spines contained the same synaptic machineiy as already present spines

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On the experiment day, animals received their peptide treatments (intracerebroventricular injection

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