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Adding a potent epigenetic modulator on top of a sluggish methylation system is not a controlled experiment

If ever needed again I will definitely be returning

Physiology 35, 302327
PXR then forms a complex with the retinoid X receptor (RXR), binds to DNA upstream of target genes, recruits coactivator (which binds to the TATA box binding protein, TBP), and activates transcription by RNA polymerase II (RNAP II)

Dempsey, P

doi: 10.1186/s13058-015-0632-x 105 MerloACasaliniPCarcangiuMLMalventanoCTriulziTMnardSet al
