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By targeting both glucagon-like peptide-1 and glucose-dependent insulinotropic peptide receptors, tirzepatide reduces hunger signals, slows gastric emptying, and improves insulin sensitivitymechanisms supported by Phase 3 SUMO clinical trials showing 22.5% weight reduction over 68 weeks

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Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, et al

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When human and rhesus monkey sequences were compared, a single difference was found in one amino acid
